Non-Invasive C3-R Corneal Cross-Linking in Los Angeles

20-Year Anniversary of Holcomb C3-R® -The World’s Longest Non-Invasive Cross-Linking Track Record and Olympic Gold Medal Behind it
If you ever wanted to go to bed and not worry about your vision getting worse or needing a cornea transplant in the future, then this may be the most important message you’ve ever read. Now you can experience the explosive burst of self-confidence from stabilized keratoconus. Imagine your day without the worry that you might go blind from keratoconus. At last, you would be free and full of confidence to tackle any challenge that life threw at you. You could finally and confidently live your life without doubting yourself and your abilities.

Impossible? Not if you believe in the “miracle of modern medicine” and what so many people are now saying after having their keratoconus treated. My name is Brian Boxer Wachler, M.D. and I’ve dedicated my career as a pioneering eye surgeon to try to rid the world of keratoconus. I’ve published three best-selling books on the topic, delivered hundreds of scientific lectures around the world, and treated thousands upon thousands of good people just like you from all across the United States and the world since 1999.

Candidates for Keratoconus Treatment

I see people like you in my practice virtually every day and I am a very good listener. Do any of these visual conditions describe you?

  • Do your nighttime halos and glare make you afraid to drive at night?
  • Did you go in for LASIK, but were surprised to find out you have Keratoconus?
  • Are you concerned about your Keratoconus getting worse in the future?
  • Are you worrying about a cornea transplant in your future?
  • Did your eye doctor say, “Just wait until you need a cornea transplant”? or “Nothing can be done”?
  • Has your doctor not told you about other options such as Holcomb C3-R® and Intacs®?

Why You Should Not Put Off Keratoconus Treatment

I have treated thousands of patients just like you. A couple whose teenage son had keratoconus delayed seeking treatment resulting in the loss of most of his vision in both eyes. I had another patient who believed her eye doctor when he told her that hard contact lenses hold back keratoconus. Sadly, that was not the case and she lost vision year after year while her eye doctor kept cashing in by updating her contact lenses. Another patient was told he had keratoconus but his eye doctor simply said, “There isn’t much you can do but wait until it gets bad enough for a cornea transplant.” He lost more vision over the years by waiting. These are a few of the thousands of stories I’ve heard over the years – people whose keratoconus was holding them back from realizing their hopes and dreams.
keratoconus progression

Risks of Not Treating Keratoconus

Keratoconus is unpredictable and progressive. Holcomb C3-R® is recommended at a minimum to strengthen your cornea and help prevent future vision loss. If your keratoconus isn’t bad right now, this is the time to do something before it gets worse. Your corneas will continue to bulge out and you will lose more vision. The risk of waiting is that as your corneas continue to bulge out and get worse, the back layer of the cornea can rip open like someone splitting their pants. When this happens to the progressively bulging cornea, the internal eye liquid rushes in and swells up the cornea resulting in 3-6 months of lost vision until this fluid dissipates. Afterward, the cornea will have a lot of new scarring, and vision will be permanently worse compared to before it ripped open. This devastating damage can easily be prevented with the 30-minute, non-invasive, 1-day recovery Holcomb C3-R®.

keratoconus cornea swelling

How C3-R® Cross-Linking Keratoconus Treatment Works

No amount of waiting can prevent keratoconus from robbing you of your future vision, but a 30-minute office procedure can! No more worrying about your future. You can once again drive with confidence…even at night with Holcomb C3-R® corneal cross-linking. In 2003, I invented a procedure that uses a proprietary vitamin B2-based cross-linking formulation applied to your cornea. The formulation is activated by a UV light device approved by FDA for use to treat medical conditions. This non-invasive treatment does not require surgery or scraping the top layer off of your cornea. Instead, it strengthens the natural anchors in your cornea and can stabilize your keratoconus in just 30 minutes. We have the longest track record worldwide with non-invasive epi-on crosslinking because we invented it.

corneal crosslinking Holcomb C3-R keratoconus

Holcomb C3-R® Cross-Linking Recovery Only Takes 1 Day

Patients typically go back to work, school, and their normal routine the day after treatment. Holcomb C3-R is typically painless, has a 99.3% success rate, has a 1-day recovery, and can prevent cornea transplants. The proprietary cross-linking solution that I developed is one of several keys to the procedure’s success. Holcomb C3-R® is protected by the United States Patent and Trademark Office. Here’s my landmark publication about Holcomb C3-R® Cross-linking (if you would like to read it in full, just click on the article below).

corneal cross linking keratoconus

Holcomb C3-R®‘s Rocky Reception

Since the first publication, I have delivered 41 scientific presentations all over the world and published three books about Holcomb C3-R ® Cross-linking. When I made my first scientific presentation about my revolutionary Holcomb C3-R® Cross-linking procedure, cornea transplant surgeons tried to destroy my reputation. They looked to discredit the new procedure that threatened the invasive, old way of treating keratoconus with cornea transplants.

Years later, I was asked to give a TEDx talk about my struggle, journey, and how I prevailed over the disinformation campaign against Holcomb C3-R® Cross-linking.

Award for Keratoconus Treatment

Holcomb C3-R – 99.3% Success Rate in Stabilization of Keratoconus

If you are having trouble finding the proper treatment for your keratoconus, then you can relate to my experience defending a revolutionary treatment. The silver bullet that shot down many of my critics was United States Olympian Steven Holcomb winning gold in the bobsled at the 2010 Vancouver Olympics. There was a worldwide tsunami of media attention after Steven’s historic win.

There was even more media coverage after he won double silver medals at the 2014 Sochi Olympics. Before he won these Olympic medals, Steven Holcomb had given up being an athlete. He was demoralized was after 12 other eye “specialists” told him he needed cornea transplants. Then his coaches and United States Olympic Team found us. Watch Steven’s powerful story of overcoming keratoconus to win Olympic gold and the historic naming of the procedure in his honor – the first time a medical procedure was named after an Olympic athlete.

Watch Award-Winning Documentary Film HOLKY about Steven Holcomb’s Amazing Life and Journey

I was fortunate to be a producer alongside Emmy-nominated documentary filmmakers who fell in love with Steven’s story and made this film honoring the greatest U.S. bobsledder of all time as told first-hand through Steven’s most powerful interview ever. HOLKY won many awards at film festivals including London Independent Film Awards, Hollywood International Golden Age Festival, and Palm Springs Shorts. It was a semi-finalist in many festivals around the world. Enjoy!

Holcomb C3-R® Cross-Linking Is Non-Invasive

Holcomb C3-R® Cross-linking System has been a routine part of our practice since 2003. With C3-R, the epithelium does not need to be removed or scraped off for crosslinking to work. Our proprietary solution penetrates the cornea with epithelium left in place. Our patients do not require multiple office visits for treatment. With non-invasive Holcomb C3-R®, both eyes are treated the same day and you can return to your normal routine the next day! If you wear contact lenses, you can put them in the next day.

Now you know why people fly here from all over the country – I’m sorry that’s not correct – from all over the world for our painless, 1-day recovery Holcomb C3-R with a 99.3% success rate and 20-year track record with Olympic gold and two Olympic silver medals behind it.

FDA Approved Holcomb C3-R® vs. Off Label Procedures

Patients Describe Epi-Off Cross-Linking in One Eye And Holcomb C3-R® in Other Eye

How is Holcomb C3-R® Customized per Eye?

1) I personally customize the energy level for each eye of each patient. I discovered that different degrees of keratoconus and patient ages require different amounts of cross-linking. As a result, another proprietary feature of Holcomb C3-R® Cross-linking is that I customize the energy level (amount of cross-linking) for each eye of each patient. I am the only doctor in the world who can do this. Other cross-linking devices only have a single, low-energy setting that they cannot change.

2) Holcomb C3-R®Cross-linking covers the greatest corneal area for cross-linking. This allows for a complete treatment of your entire cornea which is important since keratoconus extends into the periphery of your cornea. We make sure we treat your central cornea areas as well as the far periphery of your corneas with the Holcomb C3-R® Cross-linking System. This is the reason that 99.3% of people are stabilized with just a single treatment with Holcomb C3-R®.

3) Some doctors are now beginning to offer epi-on cross-linking. These treatments do not have the long track of the proprietary solution used in Holcomb C3-R®. Epi-on cross-linking must be done with higher energy levels to produce more cross-linking. Holcomb C3-R® patient customized energy levels are the reason for our 99.3% success rate. Don’t take risks with your eyes, trust your vision to the most experienced epi-on cross-linking specialist in the world.
Some Parents Won’t Allow Their Children to Have Invasive Cross-linking

Typical Results – Keratoconus Treatment Stability

c3-r keratoconus corneal cross linking stability

Don’t rely on the one-size-fits-all approach used by other cross-linking techniques. With the Holcomb C3-R® Cross-linking System you can be confident in receiving the optimized level of cross-linking treatment for each of your eyes. People with very thin corneas cannot be treated with epi-off cross-linking. Even if you have extremely thin corneas, the good news is you can still be treated with Holcomb C3-R®to strengthen your corneas and help prevent you from needing a cornea transplant.

INTACS For Keratoconus

The Holcomb C3-R® Cross-linking System can also be combined with Intacs® to flatten the keratoconus cone even more than with Intacs® alone. We routinely perform both procedures on the same day. In these cases, the Holcomb C3-R® Cross-linking System can stabilize keratoconus from getting worse as well as help the Intacs® reverse the effects of keratoconus. The combination of same-day Intacs® and the Holcomb C3-R® Cross-linking System can give you the ideal results of improved vision and stability.

corneal flattening cross-linking intacs

Holcomb C3-R® Cross-linking Candidacy

Holcomb C3-R® Cross-linking is for just about anyone who has keratoconus. People from all over the United States and other countries routinely fly here for the easy 3-day visit. I invented this procedure in 2003 and you can rest assured that coming puts you in the most experienced hands in the world with non-invasive epi-on cross-linking.

Patients Discuss Holcomb C3-R® Cross-linking

America’s Got Talent Tyce of Duo Transcend After Holcomb C3-R®

Professional Baseball Player Tommy Pham After Holcomb C3-R®

C3-R Corneal Cross-Linking FAQs

Why Didn’t My Eye Doctor Tell Me About This Treatment

In my years of experience, it’s typically one of three reasons:

  • Your eye doctor is behind the times and has never heard of Holcomb C3-R®, Intacs®, or CK.
  • Many cornea transplant surgeons don’t want you to know about Holcomb C3-R® because their practice depends on doing cornea transplants.
  • They don’t want to lose you as a patient.

Holcomb C3-R® can treat your Keratoconus and stop its worsening as it has for many others like you. The Holcomb C3-R® Cross-Linking System is the only cross-linking procedure with an Olympic gold medal behind it.

Will Holcomb C3-R® Improve My Vision?

The goal of Holcomb C3-R® is to stabilize your vision, not improve it. To improve vision I commonly use Intacs inserts to help flatten the cornea and conductive keratoplasty to further reduce your keratoconus and improve your astigmatism.

Where Can I Receive Holcomb C3-R® Cross-linking?

Holcomb C3-R® Cross-linking is special and proprietary. It is only available at our office in Beverly Hills, California. If you’re like most of our patients, you don’t live in Los Angeles and you probably don’t live in California. Most of our patients fly here from other states and even other countries.

Why Fly to Beverly Hills For Keratoconus Treatment?

You may be able to find someone near you who offers invasive epi-off cross-linking or epi-on cross-linking procedures. The reason that 25-30 people every month hop on a plane for the easy 3-day trip is that they trust the doctor who invented these procedures with the longest track record in the world. We deeply appreciate the trust that leads so many people here from all over the world since 1999. My staff and I don’t take that privilege lightly because people’s futures are in our hands, literally. That is the reason we are so detailed about every step of the way.

cross linking pros and cons keratoconus

Out-of-Town Patients

If you live out of town, that’s not a problem. I am are happy to help by providing a complimentary record review prior to you scheduling an appointment.

When you contact us, you will receive your own personal keratoconus counselor to assist you with this process. Your keratoconus counselor will coordinate a review of your records with me. Then your keratoconus counselor will personally contact you to discuss my preliminary recommendations. Then when you are ready, your keratoconus counselor will help you schedule a visit for the exam, treatment, and follow-up exam all within the same easy 3-day visit.

Your keratoconus counselor can also help coordinate your local follow-up doctor. Think of your keratoconus counselor as virtually being with you every step of the way, by your side, from your initial contact with the office through the return home for your follow-up care.

Complimentary Record Review

If you’d like Dr. Brian to review your eye records to see how he can help you, here’s how:

  1. Request a copy of your most recent eye exam from your eye doctor – be sure they include your manifest refraction (prescription) with best corrected vision.
  2. Request a copy of your most recent cornea map (topography), if available.
  3. Write a brief cover letter explaining your current vision and situation.
  4. Include on the cover letter the best phone number and e-mail to contact you.
  5. Scan and e-mail to:

Mail to: Boxer Wachler Vision Institute Keratoconus Record Review

465 N. Roxbury Drive, Suite 902 Beverly Hills, CA 90210

Or you can scan your records and email them to